Status Asthmaticus

Definition

The state asthmaticus represents the maximal form of the asthma, this one is defined as a heavy asthma without interruption with a vital threat of the patient over hours or days. The patient in the state asthmaticus must be immediately looked after intensive medically in a clinic!

Therapy of the state asthmaticus

Because of a threatening respiratory depression at the COPD patient, its breath impulse as in the case of the lung healthy one oxygen gift carefully doesn't depend on the carbon dioxide partial pressure but on the oxygen partial pressure. Fehlender Atemantrieb!

2) intensive care unit: Monitoring of heart/circulation and lung function, water and electrolyte metabolism
3) short effective beta 2-mimetic: initial 4 piston strokes

Take into account:
Itself the further application of beta sympathomimetic isn't harmless at over-dosage of beta 2-sympathomimetic gone ahead by the patient since it can come to tachykarden dysrhythmias, hypokalemia etc.. A parenteral therapy with beta sympathomimetic only at younger patients with heart rate < 130/min, e.g. Reproterol (Bronchospasmin ®), 1 ampule = 1 ml slowly, far supply by infusions (a middle adult dose = 1 ml /h)

4) means of the choice: Theophylline and/or beta 2-Sympathomimetika or sc .-additive effects at combination

5) Glycocorticoide: long latency up to the complete effect but membrane stabilizing early effect after minutes, receptor switched late effect still after several hours

6) ways of solid mucostase up to almost complete secretion transfer of the respiratory systems: Expektorantien: Secretolytics and Mucinolytics (Mucosolvan, ACC)+sufficiently parenteral fluid supply by infusions

7) at suspicion of infection asthma Antibiotic

8) Evtl. the apparatus IV controlled artificial respiration (C PAP), endoscopic suction, bronchial lavage and possible use of ketamine (Ketanest ®) or halothane general anaesthesia as ultima reason to Broncholyse

9) prophylaxis of a stomach stress ulcus by acid blocking with proton pump inhibitors

Caution in the asthma attack:
Digitalises avoid antitussives, beta blocker, acetylsalicylic acid (aspirin), sedatives (respiratory depression), parasympathomimetics (Pilokarpin carbachol etc.), subclavian artery catheter (pneumothorax danger increased) if possible!


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