Immune complex type

Type 3: Allergies of the immune complex type

It is marked for allergies of the immune complex type the allergic reaction of the type 3 by the formation of immune complexes (allergen+antibody). Under certain conditions at antigen surplus increase-limbed complexes form from allergens and antibodies, so-calledly soluble immune complexes which spread out with blood and Lymphstrom in the whole body and get stuck in the capillary skin and joints. The immune complexes then lead about a strong activation of the complementsytems (component of the non-specific immune system) to an intense inflammation with edemata, vaskulitis and bleedings. This leads to a dissolving of the immune complexes, however, also damages the surrounding fabric. Till now, what leads to this "accumulation" isn't cleared. However, it is known that the IgG antibody is essentially involved in it.

The immune system is not able always to neutralize the immune complexes completely. A deposit of the "supernumerary" immune complexes is typical of this form of the allergic reaction in certain fabrics. They then lead to allergic inflammation reactions there. However, the symptoms of an allergy don't immediately appear. It already needs a couple of hours or also days till allergic reactions let themselves be seen. These at the immune complex type triggered reactions can be limited locally (classic example: Arthus reaction) or generalisiert (classic example: Serum sickness.)

Typical illnesses, these to this belong to type 3 are and others: Vaskulitis (vessel inflammation) serum sickness Alveolitis (inflammation of the pulmonary alveoli), farmer lungs Nephritis (inflammation of the kidneys) arthritis (inflammations of the joints):


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