Immediately type

Type 1: Allergies of the immediately type, Anaphylaktic reaction:

Allergies of the immediately type, Anaphylaktic reaction quickness and often intense reactions of the immediately type. Approximately 90 per cent of all allergies are allergies of immediately type. The symptoms appear few minutes till hours after the contact with the allergen and speak in the extreme case as hay fever, rashes or asthma, for example as an anaphylaktischer shock. It is reactions of the antigen IgE type and therefore around the "classic" reaction way at the typical hay fever with antibodies of this. The inclination towards the development of multiple allergies of the immediately type is called Atopie 1.

Typical allergic illnesses are:
Hay fever

animal hair allergy, insect bite allergies, latex allergies, house dust mite allergies, food allergy, allergies allergic to medicine (Lokalanästhetic, antibiotics) asthma, nettle rash Quincke edema, Anaphylaktic shock:

Particularly intense reactions have to be expected from Atopikern, which increased a genetic disposition for one IgE for allergens have for production at contact with one. Coordinating points for the allergic reaction are the mast cells. Mast cells are special white blood corpuscles. You belong to the defense cells which are formed in the bone marrow. Mast cells are in the loose connective tissue of all organs, also in the area of the skin and in the blood vessels. Small little bubbles, these with so-called mediators or messenger substances, are especially in the mast cells Histamin are filled.

Antibodies which fastens themselves on the mast cells produces at a contact with an allergen be IgE.These antibodies can capture and neutralize an allergen molecule. This also calls itself antigen antibody reaction. At a first contact with the allergen only some become fastened IgE antibody covered to the neutralization this one on the mast cell. This reaction step calls itself sensitization.

At the next contact with the same antigen the allergic reaction then comes to light. Antibody this can be on one single mast cell between 10,000 and 50,000, capture the allergen which serves as a trigger for an excessive distribution of Histamin celebration stapled the one on a massive scale on the mast cells IgE.By the intense reaction the mast cell bursts open really.

The symptoms are aroused by Histamin. Histamin and other inflammation mediators are the reason that the blood vessels widen strongly. Liquid flows out within seconds till minutes and they come to the formation of the typical edemata and hiveses. The blood pressure sinks. The persons affected suffer from itching, red nose, eye tears and dyspnoea.

These reactions are locally frequently restricted. An example of it is the hay fever or the nettle rash. How this is the case at an anaphylaktic shock expansion of the allergic reaction to the organism knows at one a life-threatening condition stand up. The reaction is indicated by strong blood pressure drop, a narrowing of the bronchial tubes and swellings and edemata in the area of the larynx in addition to the symptoms mentioned above, in addition, nausea, possible cramps and strong hot flushes appear.

The late reactions of the type I which are caused by mediators/messenger substances by a delayed release or new entity have to be distinguished by the immediately type mentioned here clinically, however. The latent period is here up to 6 hours. The same is the working mechanism as in the case of the immediately reaction standing up within less seconds till minutes, the symptoms, however, appear only after a longer time interval.


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