Allergy emergence

In principle emergence of an allergic reaction can Pathophysiology become every substance/in our environment to the trigger of an allergy. Most allergens are egg-white substances of animal or vegetable origin, for example of flower pollen, mites and molds. Become principle at the first allergen contact of the immune system the so-called IG formed, these are specific for a certain antigen and, to recognize this (and no-one else) for antibody. No reaction enters at first yet, however, since the allergen is still new first time. One calls this process "sensitization". Next to everybody the immune system then reacts with available specific antibodies, for contact which takes up e.g. against the flower pollen of plants at the surface of so-called mast cells (certain white blood corpuscles). Antibodies and allergen connect themselves according to the key lock principle, form a complex and induce the mast cells to tip out messenger substances which pass the allergic reaction on in the body.

The histamine which plays a decisive role in the reaction chain of the allergies is released at the mucous membranes, for example, a messenger substance. Histamine is a biologically very active substance which happens in our body everywhere. E.g. each which has grasped a stinging nettle the effect of the histamines has felt sometimes.

Histamine dilates the little blood vessels. A swelling treads liquid from the blood vessels into the fabric and arises it. To the sensitive nerve ending stronger fawn of the bronchial tubes the histamine causes an irritation (it itches), one strengthened liquid production by stimulation of the activity of the glands at the mucous membrane (the nose runs, the eye tears).


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